Hyemin Gu

Postdoctoral Researcher at Mathematics and Statistics, University of Massachusetts Amherst.

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I am a postdoctoral researcher in Markos Katsoulakis’s group at UMass Amherst, where I completed my Ph.D. in Applied Mathematics with the dissertation Robust Generative Modeling with Wasserstein Proximal Regularization. My research places machine learning models on mathematical foundations, so that their behavior can be predicted, analyzed, and controlled through the underlying theory.

Research interests. Mathematically grounded machine learning; generative modeling; stable learning algorithms; scientific applications of machine learning.

Current research directions.

  • mathematically characterizing stable learning architectures for reliable training and generalization;
  • developing generative modeling methods based on Wasserstein gradient flows and variational principles for \((f,\Gamma)\)-divergence; and
  • developing scalable computational methods for scientific applications, including single-cell dynamics and supply-chain networks.

A recurring challenge in mathematical sciences is balancing abstraction, which enables transferability across domains, with concrete problem formulations, which often drive practical advances. My long-term goal is to let mathematical theory and real-world applications continuously inform and strengthen one another.

news

Aug 12, 2026 Preprint released: Fine-Tuning Generative Models for Extreme Events via CVaR-Penalized Wasserstein Gradient Flows.
Jul 16, 2026 Preprint released: Certifying Residual Architectures from Their Primitives: A Sharp Stability Threshold.
Jun 24, 2026 PROFET, our gradient-flow-based generative framework for continuous single-cell trajectory inference, was accepted at Cell Systems.

selected publications

  1. CVaR-WGF
    Fine-Tuning Generative Models for Extreme Events via CVaR-Penalized Wasserstein Gradient Flows
    Thejani Gamage, Hyemin Gu, Zhizhen Zhang, Ziyu Chen, Markos A. Katsoulakis, and Luc Rey-Bellet
    2026
  2. Stable-ResNet
    Certifying Residual Architectures from Their Primitives: A Sharp Stability Threshold
    Hyemin Gu, Michael Tyrrell, Tuhin Sahai, and Markos A. Katsoulakis
    2026
  3. PROFET
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    PROFET Predicts Continuous Gene Expression Dynamics from scRNA-seq Data to Elucidate Heterogeneity of Cancer Treatment Responses
    Yu-Chen Cheng, Hyemin Gu, Markos A. Katsoulakis, Franziska Michor, and  others
    Cell Systems, 2026
  4. ISOMORPH
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    ISOMORPH: A Supply Chain Digital Twin for Simulation, Dataset Generation, and Forecasting Benchmarks
    Zhizhen Zhang, Hyemin Gu, Markos A. Katsoulakis, Tuhin Sahai, and  others
    2026
  5. GPA
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    Lipschitz-Regularized Gradient Flows and Generative Particle Algorithms for High-Dimensional Scarce Data
    Hyemin Gu, Panagiota Birmpa, Yannis Pantazis, Luc Rey-Bellet, and Markos A. Katsoulakis
    SIAM Journal on Mathematics of Data Science, 2024